Ladner, Robert Charles,Ley, Arthur C.,Sato, Aaron K.,Stochi, Mark
申请号:
AU2010257259
公开号:
AU2010257259B2
申请日:
2010.12.16
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
#$%^&*AU2010257259B220140619.pdf#####C:NRPonbl DCC FMTU37I)u_ 1 DOC-16/112/210 ABSTRACT Disclosed are compounds that comprise: (i) a Kunitz domain polypeptide that comprises a Kunitz domain that binds to and inhibits a protease; and (ii) a plurality of polyethylene glycol moieties attached to the Kunitz domain polypeptide. Each accessible primary amine of the Kunitz domain polypeptide can be attached to one of the moieties. Also disclosed are related methods.