CRYSTALLINE(2S,4R)-5-(5'-CHLORO-2'-FLUORO-[1,1'-BIPHENYL]-4-YL)-2-(ETHOXYMETHYL)-4-(3-HYDROXYISOXAZOLE-5-CARBOXAMIDO)-2-METHYLPENTANOIC ACID AND USES THEREOF

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专利权人:

LLC;THERAVANCE BIOPHARMA R&D IP

发明人:

HUGHES, Adam D.,FLEURY, Melissa,RAPTA, Miroslav,THALLADI, Venkat R.,FASS, Gene Timothy,SIMEONE, Michael,BALDWIN, R. Michael,BOURDET, David L.

申请号：

SG11201807591V

公开号：

SG11201807591VA

申请日:

2017.03.07

申请国别(地区):

SG

年份:

2018

代理人:

摘要：

or a pharmaceutically acceptable salt thereof, having neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising this crystalline form； methods of using this crystalline form and its soluble form (I)； and processes for preparing soluble (I) and crystalline (I′) forms.

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