Crystalline(2S,4R)-5-(5'-chloro-2'-fluoro-[1,1'-biphenyl]-4-YL)-2-(ethoxymethyl)-4-(3-hydroxyisoxazole-5-carboxamido)-2-methylpentanoic acid and uses thereof

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专利权人:

LLC;Theravance Biopharma R&D IP

发明人:

Baldwin, R. Michael,Bourdet, David L.,Hughes, Adam D.,Fleury, Melissa,Rapta, Miroslav,Thalladi, Venkat R.,Fass, Gene Timothy,Simeone, Michael

申请号：

AU2017229466

公开号：

AU2017229466A1

申请日:

2017.03.07

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

In one aspect, the invention relates to a crystalline form of the structure: or a pharmaceutically acceptable salt thereof, having neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising this crystalline form； methods of using this crystalline form and its soluble form (I)； and processes for preparing soluble (I) and crystalline (I') forms.

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中国工程科技知识中心

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