Adam D. Hughes,Melissa Fleury,Miroslav Rapta,Venkat R. Thalladi,Gene Timothy Fass,Michael Simeone
申请号:
US16582051
公开号:
US20200157061A1
申请日:
2019.09.25
申请国别(地区):
US
年份:
2020
代理人:
摘要:
In one aspect, the invention relates to a crystalline form of the structure:or a pharmaceutically acceptable salt thereof, having neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising this crystalline form; methods of using this crystalline form and its soluble form (I); and processes for preparing soluble (I) and crystalline (I′;) forms.