ACIDE (2S,4R)-5-(5'-CHLORO-2'-FLUORO-[1,1'-BIPHENYL]-4-YL)-2-(ETHOXYMETHYL)-4-(3-HYDROXYISOXAZOLE-5-CARBOXAMIDO)-2-METHYL-PENTANOIQUE CRISTALLIN ET UTILISATIONS CORRESPONDANTES

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专利权人:

LLC;THERAVANCE BIOPHARMA R&D IP

发明人:

HUGHES, ADAM D.,FLEURY, MELISSA,RAPTA, MIROSLAV,THALLADI, VENKAT R.,FASS, GENE TIMOTHY,SIMEONE, MICHAEL,BALDWIN, R. MICHAEL,BOURDET, DAVID L.

申请号：

CA3015505

公开号：

CA3015505A1

申请日:

2017.03.07

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

In one aspect, the invention relates to a crystalline form of the structure: or a pharmaceutically acceptable salt thereof, having neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising this crystalline form； methods of using this crystalline form and its soluble form (I)； and processes for preparing soluble (I) and crystalline (I') forms.

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