The present invention is related to glucocorticoid receptor agonists comprised of a compound represented by formula (1) which is 2,2,4-trimethyl-6-phenyl-1,2-dihydroquinoline derivative or a salt thereof and novel pharmacological effects of the glucocorticoid receptor agonists. In the formula (1), R 1 represents formula (2a), (3a), (4a) or (5a)； R2 represents - (CO) -R8, - (CO) O-R9, or the like； R 2 -O- is substituted at the 4- or-5-position of benzene ring A； R 3 represents a lower alkyl group； R 4 , R 5 , R 6 or R 7 represents a halogen atom, a lower alkyl group which may have a substituent, or the like； m, n, p or q represents 0,1 or the like； R 8 , R 9 or the like represents a lower alkyl group which may have a substituent, a lower alkenyl group, or the like.
