The present invention is related to glucocorticoid receptor agonists comprised of a compound represented by formula (1) which is 2,2,4-trimethyl-6-phenyl-l,2-dihydroquinoline derivative or a salt thereof and novel pharmacological effects of the glucocorticoid receptor agonists. In the formula (1) , R1 represents formula (2a), (3a) , (4a) or (5a) R2 represents -(CO)-R8, -(C0)0-R9, or the like R2-O- is substituted at the 4- or-5-position of benzene ring A R3 represents a lower alkyl group R4, R5, R6 or R7 represents a halogen atom, a lower alkyl group which may have a substituent, or the like m, n, p or q represents 0,1 or the like R8, R9 or the like represents a lower alkyl group which may have a substituent, a lower alkenyl group, or the like.
