The present invention is related to glucocorticoid receptor agonists comprised of a compound represented by formula (1) which is 2,2,4-trimethyl-6-phenyl-1,2-dihydroquinoline derivative or a salt thereof and novel pharmacological effects of the glucocorticoid receptor agonists. In the formula (1), R1 represents formula (2a), (3a), (4a) or (5a)； R2 represents —(CO)—R8, —(CO)O—R9, or the like； R2—O— is substituted at the 4- or -5-position of benzene ring A； R3 represents a lower alkyl group； R4, R5, R6 or R7 represents a halogen atom, a lower alkyl group which may have a substituent, or the like； m, n, p or q represents 0, 1 or the like； R8, R9 or the like represents a lower alkyl group which may have a substituent, a lower alkenyl group, or the like.
