Chris Brough,Robert O. Williams, III,James W. McGinity,Dave A. Miller,Justin Hughey,Ryan Bennett
申请号:
US14001098
公开号:
US20140039031A1
申请日:
2012.02.23
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present disclosure is directed to compositions and methods for formulating a pharmaceutical dosage form by forming a composition comprising acetyl-11-keto-β-boswellic acid, diindolylmethane, or curcumin with one or more pharmaceutically acceptable excipients for enhanced solubility to increase bioavailability and improve therapeutic efficacy. The composition can be processed by thermo-kinetic compounding along with conventional methods known in the art, such as hot melt extrusion, melt granulation, compression molding, tablet compression, capsule filling, film-coating, or injection molding.