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THERMO-KINETIC MIXING FOR PHARMACEUTICAL APPLICATIONS
专利权人:
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM;DISPERSOL TECHNOLOGIES, LLC
发明人:
Chris BROUGH,James W. MCGINITY,Dave A. MILLER,James C. DINUNZIO,Robert O. WILLIAMS, III
申请号:
US16866676
公开号:
US20200261473A1
申请日:
2020.05.05
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical ingredients (API) with one or more pharmaceutically acceptable excipients by thermokinetic compounding into a composite. Compositions and methods of preprocessing a composite comprising one or more APIs with one or more excipients include thermokinetic compounding, comprising thermokinetic processing the APIs with the excipients into a composite, wherein the composite can he further processed by conventional methods known in the art, such as hot melt extrusion, melt granulation, compression molding, tablet compression, capsule filling, film-coating, or injection molding.
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