Dave A. Miller;James W. McGinity;Chris Brough;James DiNunzio;Robert O. Williams
发明人:
Chris Brough,James W. McGinity,Dave A. Miller,James DiNunzio,Robert O. Williams
申请号：
US12196154
公开号：
US08486423B2
申请日:
2008.08.21
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical ingredients (API) with one or more pharmaceutically acceptable excipients by thermokinetic compounding into a composite. Compositions and methods of preprocessing a composite comprising one or more APIs with one or more excipients include thermokinetic compounding, comprising thermokinetic processing the APIs with the excipients into a composite, wherein the composite can be further processed by conventional methods known in the art, such as hot melt extrusion, melt granulation, compression molding, tablet compression, capsule filling, film-coating, or injection molding.
