BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM;DISPERSOL TECHNOLOGIES, LLC
发明人:
Chris BROUGH,James W. MCGINITY,Dave A. MILLER,James C. DINUNZIO,Robert O. WILLIAMS, III
申请号:
US16012025
公开号:
US20180360850A1
申请日:
2018.06.19
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical ingredients (API) with one or more pharmaceutically acceptable excipients by thermokinetic compounding into a composite. Compositions and methods of preprocessing a composite comprising one or more APIs with one or more excipients include thermokinetic compounding, comprising thermokinetic processing the APIs with the excipients into a composite, wherein the composite can be further processed by conventional methods known in the art, such as hot melt extrusion, melt granulation, compression molding, tablet compression, capsule filling, film-coating, or injection molding.