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Thermo-Kinetic Mixing for Pharmaceutical Applications
专利权人:
Board of Regents, The University of Texas System;INTEGRICO COMPOSITES, INC.
发明人:
Chris Brough,James W. McGinity,Dave A. Miller,James C. DiNunzio,Robert O. Williams, III
申请号:
US13942199
公开号:
US20130303630A1
申请日:
2013.07.15
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical ingredients (API) with one or more pharmaceutically acceptable excipients by thermokinetic compounding into a composite. Compositions and methods of preprocessing a composite comprising one or more APIs with one or more excipients include thermokinetic compounding, comprising thermokinetic processing the APIs with the excipients into a composite, wherein the composite can be further processed by conventional methods known in the art, such as hot melt extrusion, melt granulation, compression molding, tablet compression, capsule filling, film-coating, or injection molding.
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