A compound of formula ** (See formula) ** in which Ar is selected from the group consisting of: ** (See formula) ** in which X is CH or N； Y is S, O or NH； R3 is H, halogen, CN or -C (>； = O) -NH2； and R4 is selected from the group consisting of: a) C3-7 cycloalkyl or C3-7 cycloalkenyl, which may each be substituted with 1 to 3 substituents independently selected from the group consisting of halogen, CN, OH, CF3, NH2, -NH (C1-3 alkyl), -N (C1-3 alkyl) 2, -NHC (>； = O) - (C1-3 alkyl), -NH-C (>； = O) -O- (C1- alkyl 4), -NH-SO2- (C1-3 alkyl), C1-3 alkyl optionally substituted with 1 to 3 F, C3-7 cycloalkyl, - (C1-4 alkyl) -NH-C (>； = O) - ( C1-4 alkyl), -O-C1-3 alkyl optionally substituted with 1 to 3 F, -COOH, -C (>； = O) -O- (C1-4 alkyl), -C (>； = O) -NH2 , -C (>； = O) -NH (C1-3 alkyl) and -C (>； = O) -N (C1-3 alkyl) 2； b) C4-7 cycloalkyl optionally substituted with C1-3 alkyl, wherein in the cycloalkyl moiety, one or two methylene groups are substituted by a group independently selected from -C (>； = O) -, O, S, SO, SO2 or NR7, where R7 is H, -C (>； = O) -O- (C1-4 alkyl), -C (>； = O) -NH- (C1-4 alkyl), -C (>； = O) -N (C1-4 alkyl) 2, -SO2- (C1-3 alkyl), -SO2-NH- (C1-3 alkyl), -SO2-N (C1-3 alkyl) 2, or C1- alkyl 5 optionally substituted with 1 to 3 F and / or a CN, OH or heterocyclyl； and c) a selected cycle of: ** (See formula) ** ...Un compuesto de fórmula **(Ver fórmula)** en la que Ar se selecciona del grupo que consiste en: **(Ver fórmula)** en los que X es CH o N； Y es S, O o NH； R3 es H, halógeno, CN o -C(>；=O)-NH2； y R4 se selecciona del grupo que consiste en: a) cicloalquilo C3-7 o cicloalquenilo C3-7, que puede estar cada uno sustituido con 1 a 3 sustituyentes independientemente seleccionados del grupo que consiste en halógeno, CN, OH, CF3, NH2, -NH(alquilo C1-3), -N(alquilo C1-3)2, -NHC(>；=O)-(alquilo C1-3), -NH-C(>；=O)-O-(alquilo C1-4), -NH-SO2-(alquilo C1-3), alquilo C1-3 opcionalmente sustituido con 1 a 3 F, cicloalquilo C3-
