Compound of Formula (I): ** Formula ** or salt form, stereoisomer, tautomer, crystalline, polymorph, amorphous, solvate, hydrate or ester thereof, in which X1 and X2, respectively, are selected from the group consisting of -CH2- and -CH2-, -CH2- and -O-, -O- and -CH2-, -CH2- and -N (R4) -, -N (R4) - and -CH2 -, -CH2- and -S-, -S- and -CH2-, -CH2- and -S (O) -, -S (O) - and -CH2-, -CH2- and -SO2-, -SO2 - and -CH2-, -C (O) - and -CH2-, -CH2- and -C (O) -, -C (O) - and -N (R4) -, -N (R4) - and - C (O) -, -C (O) - and -S- and -S- and -C (O) -； X3 and X4, respectively, are selected from the group consisting of -CH2- and -CH2-, -CH2- and -C (O) - and -C (O) - and -CH2-； R1 is selected from the group consisting of amino C1-4 alkyl, (C1-4 alkyl) amino C1-4 alkyl, (C1-4 alkyl) 2amino C1-4 alkyl, (C1-4 alkyl) 3amino C1-4 alkyl, formylamino C1-4 alkyl, arylcarbonylamino C1-4 alkyl, aminosulfonylamino C1-4 alkyl, aryl C1-4 alkylamino C1-4 alkyl, C1-4 cycloalkylcarbonylamino C1-4 alkyl, C3-14 cycloalkyl C1-4 alkenylcarbonylamino C1-4 alkyl , aryl C 1-4 alkylcarbonylamino C 1-4 alkyl, aryl C 2-4 alkenylcarbonylamino C 1-4 alkyl, aryl C 2-4 alkynylcarbonylaminoC 1-4 alkyl, arylsulfonylaminoC 1-4 alkyl, heterocyclylcarbonylaminoC 1-4 alkyl, heterocyclyl-alkylC 1-4 alkyl C1-4, heterocyclyl alkenylcarbonylamino C1-4 alkyl C1-4, heteroarylcarbonylamino C1-4 alkyl, heteroaryl alkenylcarbonylamino C1-4 alkyl, aminoimino, hydroxyaminoimino, (C1-4 alkyl) aminoimino, (C1-4 alkyl) 2aminoimino and aminoaminoimino, in which each occurrence of aryl is optionally substituted with one or two substitutes n halogen； R2 is absent or is a halogen substituent.Compuesto de Fórmula (I):**Fórmula** o forma de sal, de estereoisómero, de tautómero, cristalina, polimorfa, amorfa, de solvato, de hidrato o de éster del mismo, en el que X1 y X2, respectivamente, están seleccionados del grupo que consiste en -CH2- y -CH2-, -CH2- y -O-, -O- y -CH2-, -CH2- y -N(R4)-, -N(R4)- y -CH2-, -CH2- y -S-, -S- y -CH2-, -C
