An indenone derivative of formula (1) or a pharmaceutically acceptable salt thereof: ** Formula ** wherein, n is 0, 1 or 2； X is one or more substituents introduced in ortho, meta or para position of the phenyl group, each independently selected from the group consisting of hydrogen, halogen, -CN, -CF3, C1-6 alkyl, C1-6 alkoxy, C3 cycloalkyl- 10 and C3-8 cycloalkoxy； R1 is C6-10 aryl substituted with at least one substituent selected from the group consisting of halogen, oxo, - CF3, -CN, amino, hydroxy, carboxy, carbamoyl, nitro, thiol, C1-6 alkyl, C2-6 alkenyl, C1-6 alkoxy, C3-10 cycloalkyl, C3-8 cycloalkoxy, C6-10 aryl, C6-10 aryloxy, -C (O) R4, -C (O) OR4, -C (O) NR4R5, -S (O ) R4, -S (O2) R4, -S (O2) NR4R5, -NR4R5 and -NR4C (O) R5, each R4 and R5 being independently hydrogen, C1-6 alkyl or C3-10 cycloalkyl, or heteroaryl of 5 to 10 members； Y is CH, N, N + (- C1-6 alkyl) or N + (- O-)； and R2 and R3 are each independently hydrogen, C1-6 alkyl, C1-6 alkoxy, C6-10 aryl, or 5-10 membered heteroaryl or are fused together with Y to form C3-10 cycloalkyl or 5-10 heterocycloalkyl members； wherein the C6-10 aryl of R2 and R3, 5-10 membered heteroaryl, C3-10 cycloalkyl and 5-10 membered heterocycloalkyl are each independently and are optionally substituted with at least one substituent selected from the group consisting of halogen, oxo, -CF3, -CN, amino, hydroxy, carboxy, carbamoyl, nitro, thiol, C1-6 alkyl, C2-6 alkenyl, C1-6 alkoxy, C3-10 cycloalkyl, C3-8 cycloalkoxy, C6- aryl 10, C6-10 aryloxy, -C (O) R4, -C (O) OR4, -C (O) NR4R5, -S (O) R4, -S (O2) R4, -S (O2) NR4R5, - NR4R5 and -NR4C (O) R5, each R4 and R5 being independently hydrogen, C1-6 alkyl or C3-10 cycloalkyl.Un derivado de indenona de fórmula (1) o una sal farmacéuticamente aceptable del mismo:**Fórmula** en la que, n es 0, 1 o 2； X es uno o más sustituyentes introducidos en posición orto, meta o para del grupo fenilo, cada uno seleccionado independientemente del grupo que consiste en hidrógeno, halógeno, -C
