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環烷衍生物及其使用
专利权人:
LIMITED;DAIICHI SANKYO COMPANY
发明人:
SHINOZUKA, TSUYOSHI,筱塚刚,篠塚剛,KOBAYASHI, HIROYUKI,小林宏行,SUZUKI, SAYAKA,铃木沙也加,鈴木沙也加,TANAKA, KYOSUKE,田中教介,KIMOTO, HIROKO,木本裕子,DOMON, YUKI,土门友纪,土門友紀
申请号:
TW102104725
公开号:
TWI612042B
申请日:
2013.02.07
申请国别(地区):
TW
年份:
2018
代理人:
摘要:
Provided is a remedy and/or a preventive for pain, or a remedy and/or a preventive for sodium channel-mediated diseases.Provided is a compound represented by following formula (I) or a pharmacologically acceptable salt thereof.Ar1, Ar2: heteroaryl, aryl; R1, R2, R3: hydrogen, halogen, C1-C6 alkyl, halogenated C1-C6 alkyl, hydroxyl C1-C6 alkyl, C1-C6 alkoxy C1-C6 alkyl or C3-C7 cycloalkyl, cyano; R4, R5: hydrogen, halogen, C1-C6 alkyl, halogenated C1-C6 alkyl, hydroxyl, hydroxy C1-C6 alkyl, C1-C6 alkoxy C1-C6 alkyl, C3-C7 cycloalkyl, C1-C6 alkoxy; n: integer of 1 to 3; heteroaryl and aryl may have 1 or 2 group independently selected from halogen, C1-C6 alkyl, halogenated C1-C6 alkyl, hydroxyl, hydroxy C1-C6 alkyl, C1-C6 alkoxy C1-C6 alkyl, C3-C7 cycloalkyl, carboxyl, cyano, amino, C1-C3 alkyl amino, di-C1-C3 alkyl amino, and it may be the same or different if there are 2 group.
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来源网址:
http://www.ckcest.cn/home/

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