CYCLOSPORIN ANALOGUAL MODULES MODIFIED BY AMINO ACID 1 AND 3

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专利权人:

Inc.;ContraVir Pharmaceuticals

发明人:

URE, Daren R.,HEGMANS, Alexander,FENSKE, Bruce, W.,TREPANIER, Dan, J.,ABEL, Mark, D.,SUGIYAMA, Shin

申请号：

DK11848865

公开号：

DK2651965T3

申请日:

2011.12.14

申请国别(地区):

DK

年份:

2019

代理人:

摘要：

Analogues of cyclosporin-A are disclosed comprising modifications of the substituents as the positions of amino acids 1 and 3, according to the following Formula (I). The disclosed compounds include compounds having affinity for cyclophilin, including cyclophilin-A, and reduced immunosuppressivity in comparison with cyclosporin-A and analogs thereof modified solely at position 1.

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中国工程科技知识中心

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http://www.ckcest.cn/home/