KIM, SUNG WUK,KIM, HONG WOO,YOO, SANG HEE,LEE, JI SUN,HEO, HYE JIN,LEE, HONG BUM,KOOK, JI AE,LEE, YOUNG WOO
申请号:
CA2984119
公开号:
CA2984119A1
申请日:
2015.04.30
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention relates to guanidine compounds for inhibiting mitochondrial oxidative phosphorylation (OXPHOS) and use thereof. More specifically, the present invention relates to a pharmaceutical composition for preventing or treating a OXPHOS-related disease, particularly cancer by inhibiting mitochondrial oxidative phosphorylation and reprogramming cellular metabolism.