KIM, Sung Wuk,KIM, Hong Woo,YOO, Sang Hee,LEE, Ji Sun,HEO, Hye Jin,LEE, Hong Bum,KOOK, Ji Ae,LEE, Young Woo
申请号:
EP15890798
公开号:
EP3288918A4
申请日:
2015.04.30
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The present invention relates to guanidine compounds for inhibiting mitochondrial oxidative phosphorylation (OXPHOS) and use thereof. More specifically, the present invention relates to a pharmaceutical composition for preventing or treating a OXPHOS-related disease, particularly cancer by inhibiting mitochondrial oxidative phosphorylation and reprogramming cellular metabolism.