Sung Wuk Kim,Hong Woo Kim,Sang Hee Yoo,Ji Sun Lee,Hye Jin Heo,Hong Bum Lee,Ji Ae Kook,Young Woo Lee
申请号:
US15569584
公开号:
US10590081B2
申请日:
2015.04.30
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention relates to guanidine compounds for inhibiting mitochondrial oxidative phosphorylation (OXPHOS) and use thereof. More specifically, the present invention relates to a pharmaceutical composition for preventing or treating a OXPHOS-related disease, particularly cancer by inhibiting mitochondrial oxidative phosphorylation and reprogramming cellular metabolism.