Dong Cho Han;Dae Seop Shin;Young Min Han;Byoung Mog Kwon
发明人:
Byoung Mog Kwon,Dong Cho Han,Dae Seop Shin,Young Min Han
申请号：
US13891837
公开号：
US08716288B2
申请日:
2013.05.10
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to a novel pharmaceutical composition of benproperine derivatives for preventing and treating angiogenesis-related diseases. The benproperine derivatives and pharmaceutically acceptable salts thereof according to the present invention inhibit cancer cell migration and the angiogenesis of vascular endothelial cells, and therefore can be effectively used not only as an anticancer agent, but also as an agent for preventing and treating diseases caused by abnormal angiogenesis, such as diabetic retinopathy and corneal transplant rejection.
