AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A.
发明人:
MARIA ALESSANDRA ALISI,NICOLA CAZZOLLA,PATRIZIA DRAGONE,GUIDO FURLOTTI,CATERINA MAUGERI,ROSELLA OMBRATO,FRANCESCA MANCINI
申请号：
ARP130100502
公开号：
AR090086A1
申请日:
2013.02.19
申请国别(地区):
AR
年份:
2014
代理人:
摘要：
Claim 1: compounds of 1H - indazol - 3 - carboxamide which have the General formula (1), in which r u1d43 and r u1d43, identical or different,A Hydrogen Atom, a Halogen Atom, an alkyl group, a Hydroxy Group； c u2081 u208b u2086, alquenilo c u2082 u208b u2086, alquinilo c u2082 u208b u2086 and alkoxy c u2081 u208b u2086,Optionally substituted with one or more substituents selected from the group consisting nh u2082 - Halogen, Hydroxy, alkoxy, and c u2081 u208b u2083； a carboc u00edclico or Heterocyclic ring,Aliphatic or Aromatic, with 3 to 12 members, optionally substituted with one or more substituents selected from the group consisting c u2081 u208b u2086 Halogen, alkyl, Hydroxy,C u2081 u208b u2086 nr u00b9r u00b2 alkoxy -, - C (o) Oh, - C (o) - C (o) or u00b9 and nr u00b9r u00b2； and is a Link, an alkyl group or c u2081 u208b u2086, alquenilo c u2082 u208b u2086 alquinilo c u2082 u208b u2086,Optionally substituted with one or more substituents selected from the group consisting of halogen, hydroxy - nh u2082,And c u2081 u208b u2083 alkoxy； r u1d47 is a c u2081 u208b u2086 alkoxy Group； - C (o) Oh, - C (o) - or u00b9； no u2082 - NHC (； OR) r u00b9； r u00b9 and R u00b2 are independently a hydrogen Atom, an alkyl group c u2081 u208b u2084, a group alquenilo c u2082 u208b u2084,A alquinilo c u2082 u208b u2084 Group, a phenyl Group, and their Addition salts with Organic and inorganic acids and bases pharmaceutically acceptable.Reivindicación 1: Compuestos de 1H-indazol-3-carboxamida que presentan la fórmula general (1), en la que Rᵃ y Rᵃ, iguales o diferentes entre sí, son un átomo de hidrógeno； un átomo de halógeno； un grupo hidroxi； un grupo alquilo C₁₋₆, alquenilo C₂₋₆, alquinilo C₂₋₆ y alcoxi C₁₋₆, opcionalmente sustituidos con uno o más sustituyentes seleccionados de entre el grupo que consiste en halógeno, hidroxi, -NH₂, y alcoxi C₁₋₃； un anillo carbocíclico o heterocíclico, alifático o aromático, que presenta de 3 a 12 miembros, opcionalmente sustituido con uno
