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HIDROXI u00c1CIDO Derivatives, a process for their Preparation and Pharmaceutical compositions containing them
专利权人:
LES LABORATOIRES SERVIER (SOCIÉTÉ ANONYME);VERNALIS (R&D) LTD.
发明人:
GNES PROSZENYK,SZABOLCS SIPOS,JAMES BROOKE MURRAY,JAMES EDWARD PAUL DAVIDSON,OLIVIER GENESTE,MAA CHANRION,ANDRS KOTSCHY,BALZS BLINT,ATTILA PACZAL,ZOLTN SZLVIK
申请号:
ARP160101882
公开号:
AR105104A1
申请日:
2016.06.23
申请国别(地区):
AR
年份:
2017
代理人:
摘要:
Medicines.Claim 1: Compound of formula (1), in which: a represents the group of formula (2), which is attached to the Oxygen Atom 1 and 2 is attached to the phenyl Ring; r u00b9 c u2081 u208b u2086 represents a linear or branched alkyl group, a group alquenilo c u2082 u208b u2086 linear or branched, a group Alquinilo c u2082 u208b u2086 linear or branched alkoxy Group c u2081 u208b u2086, a linear or branched alkyl group, a - S - c u2081 u208b u2086,A polihaloalquilo c u2081 u208b u2086 linear or branched, a Hydroxy Group, a group hidroxialquilo c u2081 u208b u2086, a cyano Group, nr u00b9 u00b2r u00b9 u00b2 cy u2075 -, -, or a Halogen Atom; R u00b2, r u00b3, r u2074 r u2075 independently of each other and represent a hydrogen Atom, a Halogen Atom, an alkyl group C u2081 u208b u2086 linear or branched, a group alquenilo c u2082 u208b u2086 linear or branched, a group Alquinilo c u2082 u208b u2086 linear or branched.A polihaloalquilo c u2081 u208b u2086 linear or branched, a Hydroxy Group, a group hidroxialquilo c u2081 u208b u2086 c u2081 u208b u2086 alkoxy Group, a linear or branched alkyl group, a - S - c u2081 u208b u2086, a cyano Group, a Nitro Group, c u2080 u208b u2086 nr u00b9 u2070r u00b9 u2070 - alkyl -, - or - - - nr u00b9 u2070r u00b9 u2070 c u2081 u208b u2086 alkyl, o-alkyl R u00b9 u00b9 c u2081 u208b u2086 -, - C (o) - or u00b9 u2070, or r u00b9 u2070 - C (o) -, - C (o) - nr u00b9 u2070r u00b9 u2070 nr u00b9 u2070 -, - C (o) - r u00b9 u2070 nr u00b9 u2070 -, - C (o) - - - nr u00b9 u2070 c u2081 u208b u2086 or u00b9 u2070 alkyl, - C (o) - r u00b9 u2070, - nr u00b9 u2070r u00b9 u2070 SO u2082 -, alkyl - SO u2082 c u2081 u208b u2086,Or substituents of the Pairs (R u00b2, r u00b3), (r u00b3, r u2074), (r u2074, r u2075) when grafted on two adjacent carbon ATOMS, form together with the carbon Atoms are bonded to an Aromatic Ring or Aromatic Compound by 5 to 7 members in the ring, PU DTS contain 1 to 3 heteroatoms selected from Oxygen, Sulfur and NitrogenSinc
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