БОЕР Жак Ален (CH),САЛЬВАНЬИ Марко (CH),ВИГРУ Жан-Пьер Леон (FR),ШАЛВЕ Летисия Леела Жизель (FR),КЬЯВАРОЛИ Карло (FR)
申请号：
RU2011112781/15
公开号：
RU2011112781A
申请日:
2008.09.04
申请国别(地区):
RU
年份:
2012
代理人:
摘要：
1. An extract of one or more bacterial strains of Lactobacillus, where the extract is a soluble extract, and where the extract contains chemically modified bacterial molecules. ! 2. The extract according to claim 1, where the chemically modified bacterial molecules are obtained by exposure to an alkaline environment on one or more bacterial strains of Lactobacillus. ! 3. The extract according to claim 1, where the extract has immunomodulatory activity in an individual. ! 4. The extract according to claim 3, where the extract has immunostimulating activity in an individual. ! 5. The extract according to claim 3, where the extract has anti-inflammatory activity in an individual. ! 6. The extract according to claim 1, where one or more bacterial strains of Lactobacillus contains one or more of Lactobacillus fermentum, Lactobacillus rhamnosus, Lactobacillus plantarum, Lactobacillus johnsonii, Lactobacillus helveticus, Lactobacillus casei defensis, Lactobacillus casei. casei, Lactobacillus paracasei, Lactobacillus bulgaricus, Lactobacillus paracasei, Lactobacillus acidophilus, Lactobacillus reuteri, Lactobacillus salivarius, Lactobacillus lactis and Lactobacillus delbrueckii. ! 7. The extract according to claim 1, where one or more bacterial strains of Lactobacillus contains one or more of Lactobacillus fermentum I-3929, Lactobacillus rhamnosus 71.38, Lactobacillus plantarum 71.39, Lactobacillus johnsonii 103782 and Lactobacillus helveticus 103146.! 8. The extract according to claim 1, where one or more of aspartic acid, glutamic acid, serine, histidine, alanine, arginine, tyrosine, methionine, phenylalanine and lysine in the extract are racemicized by at least 10%. ! 9. The extract according to claim 1, where the extract is able to achieve the calculated ratio of IL10 / IL12 in mononuclear cells of human peripheral blood, and the ratio is equal to or greater than the ratio of IL10 / IL12 achieved by the live strain of Lactobacillus from which the extract is obtained. !
