A wrist orthosis (1) for support of a patient’s wrist, comprising a wire frame (2) for engagement with a forearm (F), wrist (W), and hand (H) of a patient, the wire frame (2) comprising a radial wire 5 section (3) configured to extend in a distal direction along the forearm, wrist and toward a radial side ofthe hand. The radial wire section (3) is connected to a palmar wire section (4) configured to extend in lateral direction from the radial side ofthe hand along a palmar region (6) thereoftoward an ulnar side of the hand. The palmar wire section (4) is connected to an ulnar wire section (5) configured to extend from the ulnar side of the hand in proximal direction toward an along the wrist 10 and forearm. The radial and ulnar wire sections (3,5) are laterally spaced apart along an intermediate dorsal region (7) ofthe hand. [Figure 2]