КУЛИОПУЛОС Атан (US),МакМАРРИ Томас Дж. (US),КОВИК Лидия (US),ЧЕРНЫШЕВ Борис (US)
申请号：
RU2011122647/04
公开号：
RU2011122647A
申请日:
2009.11.04
申请国别(地区):
RU
年份:
2012
代理人:
摘要：
1. A compound represented by formula A: or a pharmaceutically acceptable salt thereof, wherein: L is a linking group represented by C (O) and associated with the N-terminal nitrogen groups X or the following amino acid residue present if Xotsutstvuet T is a lipophilic pegging group bonded to L and Ryavlyaetsya ORili N (R), each Ryavlyaetsya independently H or alkyl, wherein there are at least three adjacent X-Xaminokislotnyh residue, and wherein: Xyavlyaetsya valine residue or absent, Xyavlyaetsya isoleucine residue or absent, Xyavlyaetsya leucine residue or absent, Xyavlyaetsya valine residue, a glycine residue or absent, Xyavlyaetsya methionine residue, isoleucine residue, leucine residue, norleytsinovym residue, a serine residue, an alanine residue, d-methionine residue, d-serine residue or ots utstvuet, Xyavlyaetsya glycine residue, an alanine residue, a histidine residue, a lysine residue or absent, Xyavlyaetsya tyrosine residue, alanine residue, d-tyrosine residue, arginine residue or absent, Xyavlyaetsya glutamine residue, an alanine residue, d-glutamine residue, a methionine residue, threonine residue or a lysine residue or absent, Xyavlyaetsya lysine residue, d-lysine residue, an alanine residue or absent, Xyavlyaetsya lysine residue, d-lysine residue leucyl new residue, threonine residue, an alanine residue or absent, leucine residue Xyavlyaetsya, d-a leucine residue, an alanine residue, an isoleucine residue serine residue, a cysteine residue, an arginine residue
