The present invention provides use of a green mango extract for manufacture of a pharmaceutical composition for reducing fat accumulation and oxidative damage in liver cells. The present invention also provides use of compounds, isolated from the green mango extract and identified as hydrolyzed tannins, for manufacture of a pharmaceutical composition for reducing fat accumulation in liver.本發明提供一種芒果幼果萃取物用於製備減少肝細胞脂肪累積及氧化傷害之醫藥組合物之用途。本發明亦提供一種分離自該芒果幼果萃取物的水解單寧化合物用於製備減少肝臟脂肪累積之醫藥組合物之用途。