The present invention provides a use of green mango extract in the manufacture of a medicament for promoting heat producing in fat cells. The green mango extract significantly inhibits lipogenesis, reduces the size of fat cells, activates PPARγ and UCP-1 gene expression, and promotes heat producing in fat cells. Further, the green mango extract can turn white fat cells which storing fat into brown fat cells for fat metabolism.本發明提供一種芒果幼果萃取物用於製備促進脂肪細胞產生熱量之醫藥組成物的用途。該芒果幼果萃取物顯著抑制脂肪生成、使脂肪細胞體積變小、並活化PPARγ與UCP-1之基因表現,具有促進脂肪細胞產生熱量的效果,進一步可將儲存脂肪的白色脂肪細胞轉變為代謝脂肪的褐色脂肪細胞。
