FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to new dihydropyran-2-one of formula, where R1 is selected from hydrogen, ORa, OCORa, OCOORa, NRaRb, NRaCORb and NRaC(NRa)NRaRb each R2 and R3 are optionally selected from hydrogen, substituted or unsubstituted C1-C12 alkyl, substituted or unsubstituted C2-C12 alkenyl and substituted or unsubstituted C2-C12 alkynyl each R41, R42, R43, R44, R45, R46, R47 and R48 are optionally selected from hydrogen, substituted or unsubstituted C1-C12 alkyl, substituted or unsubstituted C2-C12 alkenyl and substituted or unsubstituted C2-C12 alkynyl each R5, R6 and R7 are optionally selected from hydrogen, CORa, COORa, substituted or unsubstituted C1-C12 alkyl, substituted or unsubstituted C2-C12 alkenyl and substituted or unsubstituted C2-C12 alkynyl, or R5 and R48 together with coupled atom N and atom C whereto attached can form substituted or unsubstituted heterocyclic group each Ra and Rb are optionally selected from hydrogen, substituted or unsubstituted C1-C12 alkyl, substituted or unsubstituted C2-C12 alkenyl, substituted or unsubstituted C2-C12 alkynyl, substituted or unsubstituted aryl and substituted or unsubstituted heterocyclic group and each dashed line means an optional additional bond to its pharmaceutically acceptable salts, tautomers or stereoisomers.EFFECT: development of the method for preparing an anticancer composition, and the method of treating cancer.46 cl, 10 tbl, 12 exИзобретение относится к новым соединениям дигидропиран-2-она формулы (I),где R1 выбирают из водорода, ORa, OCORa, OCOORa, NRaRb, NRaCORb и NRaC(NRa)NRaRb каждый R2 и R3 независимо выбирают из водорода, замещенного или незамещенного C1-C12 алкила, замещенного или незамещенного C2-C12 алкенила и замещенного или незамещенного C2-C12 алкинила каждый R41, R42, R43, R44, R45, R46, R47 и R48 независимо выбирают из водорода, замещенного или незамещенного C1-C12 алкила, замещенного или незамещенного C2-C12 алкенила и замещенного или незамещенног
