A denture base manufacturing method according to an embodiment of the present invention includes an apparatus preparing step, a cutting data creating step, and a cutting step. The apparatus preparing step involves preparing a cutting apparatus including a retainer, a cutter, and a controller. The retainer retains a workpiece material composed mainly of thermoplastic resin. The cutter cuts the workpiece material. The controller is communicably connected to the retainer and the cutter. The cutting data creating step involves creating cutting data in accordance with three-dimensional data indicative of a shape of a denture base including a fitted portion to be fitted to an abutment tooth of a patient. The cutting step involves cutting the workpiece material using the cutting apparatus in accordance with the cutting data.