PYRIDINES SUBSTITUEES EN TANT QUE BLOQUEURS DE CANAUX SODIQUES

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专利权人:

PURDUE PHARMA L.P.

发明人:

NI, CHIYOU,PARK, MINNIE,SHAO, BIN,TAFESSE, LAYKEA,YAO, JIANGCHAO,YOUNGMAN, MARK,ZHOU, XIAOMING

申请号：

CA2822789

公开号：

CA2822789A1

申请日:

2011.12.21

申请国别(地区):

CA

年份:

2012

代理人:

摘要：

The invention relates to substituted pyridine compounds of Formula I: (I) and the pharmaceutically acceptable salts, prodrugs, and solvates thereof, wherein R1a, R1b, R2a, R2b, R2c, A1, A2, and X are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula I to treat a disorder responsive to the blockade of sodium channels. Compounds of the present invention are especially useful for treating pain.

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