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Pyridine compounds and the users thereof
专利权人:
Xiaoming Zhou;Chiyou Ni;Bin Shao;Jiangchao Yao;Jianming Yu;Laykea Tafesse
发明人:
Chiyou Ni,Bin Shao,Laykea Tafesse,Jiangchao Yao,Jianming Yu,Xiaoming Zhou
申请号:
US13821732
公开号:
US09056832B2
申请日:
2011.09.16
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The invention relates to substituted pyridine compounds of Formula (I) and the pharmaceutically acceptable salts, prodrugs, and solvates thereof, wherein R1a, A1, A2, E, G, Z1, and Z2 are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula I to treat a disorder responsive to the blockade of sodium channels. Compounds of the present invention are especially useful for treating pain.
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