SUBSTITUTED PYRIDINES AS SODIUM CHANNEL BLOCKERS

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专利权人:

PURDUE PHARMA L P

发明人:

CHIYOU NI,Bin SHAO,JIANGCHAO YAO,Xiaoming ZHOU,MINNIE PARK,LAYKEA TAFESSE,MARK YOUNGMAN

申请号：

ZA201303780

公开号：

ZA201303780B

申请日:

2013.05.24

申请国别(地区):

ZA

年份:

2014

代理人:

摘要：

The invention relates to substituted pyridine compounds of Formula I: (I) and the pharmaceutically acceptable salts, prodrugs, and solvates thereof, wherein R1a, R1b, R2a, R2b, R2c, A1, A2, and X are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula I to treat a disorder responsive to the blockade of sodium channels. Compounds of the present invention are especially useful for treating pain.

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