Substituted pyridines as sodium channel blockers

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专利权人:

发明人:

Laykea Tafesse,Jiangchao Yao

申请号：

US14384534

公开号：

US09206127B2

申请日:

2013.03.15

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The invention relates to substituted pyridine and pyrimidine compounds of Formula (I) and the pharmaceutically acceptable salts, prodrugs, and solvates thereof, wherein R1, R2a, R2b, A1, A2, X, and Z are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula (I) to treat a disorder responsive to the blockade of sodium channels. Compounds of the present invention are especially useful for treating pain.

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