ВАН ЭС Элизабет Катарина Адриана Мария (NL),ГРОС-ВАН ХЕСТ Марьян (NL),ЛАБЕЙ Эрик (NL),ВЕСТЕРБЕК Йоханнес Мартинус Мария (NL)
申请号：
RU2015104792
公开号：
RU2015104792A
申请日:
2013.07.12
申请国别(地区):
RU
年份:
2016
代理人:
摘要：
1. Hypoallergenic fusion protein for use in the prevention of allergy to milk proteins or for use in the induction of oral tolerance with respect to milk proteins, where the fusion protein is selected from cross-linked casein, and their crosslinked caseinate kombinatsiy.2. Hypoallergenic fusion protein for use according to Claim. 1, wherein the milk protein is casein, caseinate, whey protein, lactoferrin, transferrin or combinations thereof, preferably casein or caseinate kombinatsiya.3. Hypoallergenic fusion protein for use according to Claim. 1 or 2, wherein the fusion protein was ligated by enzymatic treatment, preferably by treatment transglyutaminazoy.4. Hypoallergenic fusion protein for use according to Claim. 1 or 2, wherein the fusion protein comprises 0.1-2, preferably 0.5-1 per molecule of crosslinking of casein or kazeinata.5. Hypoallergenic fusion protein for use according to Claim. 1 or 2, wherein the fusion protein is administered to a human patient under the age of 36 months, preferably 12 months, more preferably up to 6 mesyatsev.6. Hypoallergenic fusion protein for use according to Claim. 1 or 2, wherein the fusion protein is administered to a human patient predisposed to develop an allergy to protein moloka.7. Nutritional composition for use in the prevention of allergy to milk proteins or for use in the induction of oral tolerance to milk proteins, wherein the nutritional composition comprises a crosslinked hypoallergenic protein selected from cross-linked casein, and their crosslinked caseinate kombinatsiy.8. Nutritional composition for use according to claim. 7 wherein the milk protein is casein, caseinate, whey protein, lactoferrin, transferrin or combinations thereof, preferably casein or caseinate kombinatsiya.9. Nutrient composition1. Гипоаллергенный сшитый белок для применения в профилактике аллергии на белки молока или для применения в индукции оральной толерантности относительно белков молока, где сшитый белок выбирают из сшитого казеина,
