RENNIE, GLEN ROBERT,BARDEN, TIMOTHY CLAUDE,LEE, THOMAS WAI-HO,IYENGAR, RAJESH R.,NAKAI, TAKASHI,MERMERIAN, ARA,JIA, JAMES,IYER, KARTHIK,IM, G-YOON JAMIE,RENHOWE, PAUL ALLAN,JUNG, JOON,GERMANO, PETER,T
申请号:
CA3042713
公开号:
CA3042713A1
申请日:
2017.11.07
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present disclosure relates to stimulators of soluble guanylate cyclase (sGC), pharmaceutical formulations comprising them and their uses thereof, alone or in combination with one or more additional agents, for treating various diseases, wherein an increase in the concentration of nitric oxide (NO) and/or an increase in the concentration of cyclic Guanosine Monophosphate (cGMP) might be desirable. Various compounds are disclosed, including those of Formula (I).