Glen Robert Rennie,Rajesh R. Iyengar,Thomas Wai-Ho Lee,Paul Allan Renhowe,Joon Jung
申请号：
US15693758
公开号：
US10472363B2
申请日:
2017.09.01
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present disclosure relates to stimulators of soluble guanylate cyclase (sGC), pharmaceutical formulations comprising them and their uses thereof, alone or in combination with one or more additional agents, for treating various diseases, wherein an increase in the concentration of nitric oxide (NO) or an increase in the concentration of cyclic Guanosine Monophosphate (cGMP), or both, or an upregulation of the NO pathway is desirable. The compounds are of Formula I:
