Oh, Sang Ho,Kim, Jong Gyun,Oh, Se-Woong,Han, Tae Dong,Chung, Soo Yong,Lee, Seong Ran,Kim, Kyeong Bae,Lee, Young Sung,Shin, Woo Seob,Ju, Hyun,Kang, Jeong Ki,Park, Su Min,Kim, Dong Kyun
申请号：
AU2018256227
公开号：
AU2018256227A1
申请日:
2018.04.18
申请国别(地区):
AU
年份:
2019
代理人:
摘要：
The present invention relates to novel mesylate salt of N-(5-(4-(4-((dimethylamino)methyl)-3-phenyl-1H-pyrazol-1-yl)pyrimidine-2-ylamino)-4-methoxy-2-morpholinophenyl)acrylamide, a novel crystalline form thereof, and a process for preparing the same. More specifically, the present invention relates to mesylate salt of N-(5-(4-(4-((dimethylamino)methyl)-3-phenyl-1H-pyrazol-1-yl)pyrimidine-2-ylamino)-4-methoxy-2-morpholinophenyl)acrylamide, which is excellent in stability, solubility, and bioavailability when it is administered not only alone but also in combination with other drugs and which has a high purity, a crystalline form thereof, and a process for preparing the same.
