Use of aminophenylbenzotriazole derivatives for protecting human and animal skin and hair from the harmful effects of uv radiation and cosmetic compositions thereof
Disclosed are-(2-Hydroxy-4-aminophenyl)benzotriazole derivatives of formula (1), wherein R1 and R4 independently of each other are hydrogen C1-C28alkyl C1-C28alkoxy C2-C28al- kenyl C2-C28alkinyl C3-C12cycloalkyl C3-C12cycloalkenyl C7-C28 aralkyl C1-C20hetero- alkyl C3-C12cycloheteroalkyl or C5-C16 heteroaralkyl and wherein C1-C28alkyl, C1-C28al- koxy, C2-C28alkenyl and C2-C28alkinyl are unsubstituted or may be substituted by at least one C1-C5alkyl, C1-C5alkoxy or hydroxy R2 and R3 independently of each other are hydrogen C1-C28alkyl C2-C28 alkenyl C2-C22alki- nyl C3-C12cycloalkyl C3-C12cycloalkenyl C7-C28 aralkyl C1-C20 heteroalkyl C3-C12cyclo- heteroalkyl C5-C16heteroaralkyl and wherein C1-C28alkyl, C1-C28alkoxy, C2-C28alkenyl and C2-C28alkinyl are unsubstituted or may be substituted by at least one C1-C5alkyl, C1- C5alkoxy or hydroxy or CO-R5 or R2 and R3 together together with the linking nitrogen form a 5- to 7-membered, monocyclic, carbocyclic or heterocyclic ring R5 is C1-C28alkyl C2-C28alkenyl C2-C28alkinyl C3-C12cycloalkyl C3-C12cycloalkenyl C7-C20aralkyl C1-C20 heteroalkyl C3-C12 cycloheteroalkyl C1-C5alkoxycarbonyl-C1- C5alkyl or C5-C16heteroaralkyl for protecting human and animal hair and skin from harmful effects of UV radiation.Linvention concerne des dérivés de (2-hydroxy-4-aminophényl)benzotriazoles de la formule (1), où R1 et R4 sont, indépendamment lun de lautre, hydrogène alkyle en C1-C28 alcoxy en C1-C28 alcényle en C2-C28 alcynyle en C2-C28 cycloalkyle en C3-C12 cycloalcényle en C3-C12 aralkyle en C7-C28 hétéroalkyle en C1-C20 cyclohétéroalkyle en C3-C12 ou hétéroaralkyle en C5-C16 et où alkyle en C1-C28 alcoxy en C1-C28 alcényle en C2-C28 alcynyle en C2-C28 sont non substitués ou peuvent être substitués par au moins un alkyle en C1-C5 alcoxy en C1-C5 ou hydroxy R2 et R3 sont indépendamment, hydrogène alkyle en C1-C28 alcényle en C2-C28 alcynyle en C2-C22 cycloalkyle en C3-C12 cycloalcényle en C3-C12 aralkyle en C7-C28 hét