use of aminophenylbenzotriazole derivatives to protect skin and humans and animals from the harmful effects of UV radiation, and cosmetic compositions of these derivatives.
use of aminophenylbenzo-triatol derivatives to protect skin and humans and animals from the harmful effects of UV radiation, and cosmetic compositions of such derivatives. The present invention relates to (2'-hydroxy-4'-aminophenyl) benzotriazole derivatives of formula R1 and R4 independently of one another are hydrogen; C1 -C28 alkyl; C1 -C28 alkoxy; c2 -C28 alkenyl; c2 -C28 alkynyl; C3 -C12 cycloalkyl; c3 c12 cycloalkenyl; C7-C28 aralkyl; C 1 -C 20 -heteroalkyl; C3 -C12 cycloheteroalkyl; or C2 -C28 alkenyl and C2 -C28 alkynyl are unsubstituted or may be substituted by at least one C1 -C5 alkyl, C1 -C5 alkoxy or hydroxy; r2 and r3m independently of each other are hydrogen; C1 -C28 alkyl; c2 -C28 alkenyl; c2 -C22 alkynyl; C3 -C12 cycloheteroalkyl; C5-C16-heteroaralkyl; and wherein C1-C28 alkyl, C1-C28 alkoxy, C2-C28 alkenyl and C2-C28 alkynyl are unsubstituted or may be substituted by at least one C1-C5 alkyl, C1-C5 alkoxy or hydroxy or co-R5; or r 2 and r 3 together with the binding nitrogen form a 5- to 7-membered monocyclic, carbocyclic or heterocyclic ring; R5 is C1 -C28 alkyl; c2 -C28 alkenyl; c2 -C28 alkynyl; C3 -C12 cycloalkyl; C3 -C12 cycloalkenyl; c7 c20 aralkyl; C 1 -C 20 -heteroalkyl; C3 -C12 cycloheteroalkyl; C 1 -C 5 alkoxycarbonyl-C 1 -C 5 alkyl; or C 5 -C 16 -heteroaralkyl; to protect human and animal skin and skin from harmful effects of UV radiation.uso de derivados de aminofenilbenzo-triatol para proteger pele e pelos humanos e animais dos efeitos danosos de radiação uv, e composições cosméticas desses derivados. a presente invenção refere-se a derivados de (2<;39>;-hidróxi-4<;39>;-aminofenil)benzotriazol de fórmula r1 e r4 um independentemente do outro, são hidrogênio; c1-c28 alquila; c1-c28 alcóxi; c2-c28 alquenila; c2-c28 alquinila; c3-c12 cicloalquila; c3 c12 cicloalquenila; c7-c28 aralquila; c1-c20-heteroalquila; c3-c12 ciclo-heteroalquila; ou c2-c28 alquenila e c2-c28 alquinila são não-substituídos ou poderão ser substituídos por pelo