CHEN, CHIN CHU,陈劲初,陳勁初,HSU, SHENG CHIEH,许胜杰,許勝傑,YEH, SHU HSING,叶淑幸,葉淑幸,CHEN, YEN PO,陈彦博,陳彥博
申请号:
TW105136605
公开号:
TWI601824B
申请日:
2016.11.10
申请国别(地区):
TW
年份:
2017
代理人:
摘要:
The present invention provides a use of Cordyceps cicadae active substances for manufacturing a composition that promotes hepatocyte proliferation. The Cordyceps cicadae active substance is prepared by the following steps: (a) culturing Cordyceps cicadae mycelia on a plate medium at 15-35 DEG C for 5-14 days (b) innoculating the cultured Cordyceps cicadae mycelia of step (a) into a flask and culturing at 15-35 DEG C, pH 2-8 for 5-12 days (c) inoculating the cultured Cordyceps cicadae mycelia of step (b) into a fermentation tank and culturing at 15-35 DEG C, pH 2-8 for 3-5 days to form a Cordyceps cicadae mycelia fermentation liquid containing the Cordyceps cicadae active substance.本發明提供一種蟬花活性物質之用途,係用於製造促進肝細胞增生之組合物。所述蟬花活性物質係經下列步驟製備:(a)取蟬花菌絲體於平板培養基上,於15-35℃培養5-14天;(b)將步驟(a)培養後之蟬花菌絲體接種至一燒瓶內,於15-35℃、pH 2-8的條件培養5-12天;(c)將步驟(b)培養後之蟬花菌絲體接種至一發酵槽內,於15-35℃、pH 2-8的條件培養3-5天,形成含有蟬花活性物質之一蟬花菌絲體發酵液。