THIMMASETTAPPA THIPPESWAMY,ANUMANTHA G. KANTHASAMY
申请号：
US15829608
公开号：
US20180153891A1
申请日:
2017.12.01
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention describes novel pharmaceutical compositions and methods for treatment of diseases, disorders, or conditions characterized by recurrent seizures, particularly, epilepsy. According to the invention, compounds which inhibit the activity or expression of non-receptor Fyn tyrosine kinase can prevent activation epileptic pathophysiology and provide protection from and treatment of epilepsy. Particularly preferred is the class of small molecule Fyn kinase inhibitors such as sacaratinib and its prodrugs, derivatives, analogs and the like.
