THE STATE OF ISRAEL; MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT; AGRICULTURE RESEARCH ORGANIZAT
发明人:
Anat ELMANN,RIVKA OFIR,YOEL KASHMAN
申请号：
US15039429
公开号：
US20170020842A1
申请日:
2014.11.26
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The invention relates to 3,5,4′-trihydroxy-6,7,3′-trimethoxyflavone (TIF) and achillolid A in prevention or treatment of Alzheimer's disease as well as other neurodegenerative diseases such as Parkinson's disease, Amyotrophic Lateral Sclerosis (ALS), ischemia, immunodeficiency virus-1 (HTV-1)-associated dementia, Lewy body associated dementia, traumatic brain injury (TBI), glioma, epilepsy. Huntington's disease, multiple sclerosis, glaucoma and schizophrenia where neuroinflammation, oxidative stress, glutamate toxicity and amyloid beta toxicity are part of the pathophysiology.
