AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER);THE STATE OF ISRAEL - MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT
发明人:
ELMANN, ANAT,OFIR, RIVKA,KASHMAN, YOEL
申请号：
EP14865412
公开号：
EP3074029A4
申请日:
2014.11.26
申请国别(地区):
EP
年份:
2016
代理人:
摘要：
The invention relates to 3,5,4′-trihydroxy-6,7,3′-trimethoxyflavone (TIF) and achillolid A in prevention or treatment of Alzheimer's disease as well as other neurodegenerative diseases such as Parkinson's disease, Amyotrophic Lateral Sclerosis (ALS), ischemia, immunodeficiency virus-1 (HTV-1)-associated dementia, Lewy body associated dementia, traumatic brain injury (TBI), glioma, epilepsy. Huntington's disease, multiple sclerosis, glaucoma and schizophrenia where neuroinflammation, oxidative stress, glutamate toxicity and amyloid beta toxicity are part of the pathophysiology.
