ELMANN ANAT;OFIR RIVKA;THE STATE OF ISRAEL MINISTRY OF AGRICULTURE AND RURAL DEVELOPMENTAGRICULTURAL RESEARCH ORGANIZATION(ARO) (VOLCANI CENTER).;KASHMAN YOEL
发明人:
ELMANN Anat,OFIR Rivka,KASHMAN Yoel
申请号：
IL24559716
公开号：
IL245597D0
申请日:
2016.05.11
申请国别(地区):
IL
年份:
2016
代理人:
摘要：
The invention relates to 3,5,4′-trihydroxy-6,7,3′-trimethoxyflavone (TIF) and achillolid A in prevention or treatment of Alzheimer's disease as well as other neurodegenerative diseases such as Parkinson's disease, Amyotrophic Lateral Sclerosis (ALS), ischemia, immunodeficiency virus-1 (HTV-1)-associated dementia, Lewy body associated dementia, traumatic brain injury (TBI), glioma, epilepsy. Huntington's disease, multiple sclerosis, glaucoma and schizophrenia where neuroinflammation, oxidative stress, glutamate toxicity and amyloid beta toxicity are part of the pathophysiology.
