The present invention relates to compounds of the formula I and in particular medicaments comprising at least one compound of the formula I for use in the treatment and/or prophylaxis of physiological and/or pathophysiological states in the triggering of which cathepsin D is involved, in particular for use in the treatment and/or prophylaxis of arthrosis, traumatic cartilage injuries, arthritis, pain, allodynia or hyperalgesia.本發明係關於式I化合物及尤其包含至少一種式I化合物之藥劑，其用於治療及/或預防觸發過程中涉及組織蛋白酶D之生理及/或病理生理學狀態，尤其用於治療及/或預防關節病、創傷軟骨損傷、關節炎、疼痛、異常疼痛或痛覺過敏。
