OH, Sang Ho,KIM, Jong Gyun,OH, Se-Woong,HAN, Tae Dong,CHUNG, Soo Yong,LEE, Seong Ran,KIM, Kyeong Bae,LEE, Young Sung,SHIN, Woo Seob,JU, Hyun,KANG, Jeong Ki,PARK, Su Min,KIM, Dong Kyun
申请号：
PH12019502370
公开号：
PH12019502370A1
申请日:
2019.10.18
申请国别(地区):
PH
年份:
2020
代理人:
摘要：
The present invention relates to novel mesylate salt of N-(5-(4-(4-((dimethylamino)methyl)-3-phenyl-1H-pyrazol-1-yl)pyrimidine-2-ylamino)-4-methoxy-2-morpholinophenyl)acrylamide, a novel crystalline form thereof, and a process for preparing the same. More specifically, the present invention relates to mesylate salt of N-(5-(4-(4-((dimethylamino)methyl)-3-phenyl-1H-pyrazol-1-yl)pyrimidine-2-ylamino)-4-methoxy-2-morpholinophenyl)acrylamide, which is excellent in stability, solubility, and bioavailability when it is administered not only alone but also in combination with other drugs and which has a high purity, a crystalline form thereof, and a process for preparing the same.
