Compounds of formula I wherein I, R represents from one to five substituentsindependently selected from hydrogen, nitro, cyano, C-C-alkyl,halogen, carboxy, amino, trifluoromethyl, hydroxy, C-C-aIkOXygroups, X is hydrogen, halo, N, SH, =O, =CH, an aromatic,preferably phenyl, ring optionally substituted by R groups asdefined above, amino, mono- or disubstituted amino groups wherein the substituentsare selected from C-C alkyl, phenyl or benzyl groups optionallysubstituted by R groups as defined above Y is hydrogen, alkyl C-C,amino, or a group of formula -(CH)A wherein A is an aromatic,preferably phenyl, ring optionally substituted by R groups asdefined above with the proviso that when X and Y are hydrogen, R cannotrepresent a 4-hydroxy or 4-alkoxy groups, are useful for the treatment of TumorNecrosis Factor mediated immunopathological conditions as well as of diseaseswhich may be treated or alleviated by inhibition of Interleukin -10 (IL-IO).
