CHEMICAL MODIFICATION OF ANTIBODIES

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专利权人:

发明人:

申请号：

EP13709522.0

公开号：

EP2822597A1

申请日:

2013.03.08

申请国别(地区):

EP

年份:

2015

代理人:

摘要：

The present invention relates to antibodies and antibody fragments, one or more of whose native inter-chain disulfide bridges have been replaced with a specific bridging moiety. The bridging moiety can be selectively targeted to inter-chain disulfide bonds within the antibody or antibody fragment, enabling the construction of more homogenously modified products such as antibody-drug conjugates.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/